The Longevity Program

Longevity - Micronutrients

Micronutrients, which include vitamins and minerals, play critical roles in maintaining health and promoting longevity. They are involved in functioning of the immune & nervous system, energy production, bone health, and DNA synthesis and repair

Longevity - Micronutrients

Micronutrients are the vitamins and minerals required by your body to maintain optimal health. These are different from macronutrients (like carbohydrates, proteins, and fats), which are needed in larger amounts. Micronutrients play critical roles in maintaining health and promoting longevity and are essential even though your body needs them in small quantities. They facilitate a range of physiological functions, including bone health, immune response, eye health, and DNA synthesis and repair.

14 Analytes Tested: Vitamin B2 (Riboflavin) Vitamin B6, Folate (Vitamin B9), Vitamin B12, Methyl Vitamin B12, Vitamin D 25-OH, Iron, Magnesium, Calcium, Potassium, Phosphorous, Copper, Zinc, Selenium

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Micronutrients Related To Longevity

  1. Vitamin D: Vitamin D plays a critical role in immune function, bone health, and inflammation regulation. Lower levels of Vitamin D have been linked to increased mortality and age-related diseases.

  2. B Vitamins: This group, which includes B6, B12, and folate, is essential for metabolic processes, red blood cell production, and the maintenance of the nervous system. They are also crucial for homocysteine metabolism; elevated homocysteine levels have been linked to an increased risk of cardiovascular diseases.

  3. Vitamin E: This antioxidant helps protect cells from damage caused by free radicals, unstable molecules that can contribute to aging and disease.

  4. Vitamin C: Also an antioxidant, Vitamin C is essential for skin health, immune function, and cardiovascular health.

  5. Iron and Age-Related Diseases: Accumulation of iron in the body can lead to oxidative stress, which contributes to the pathogenesis of numerous age-related diseases, including cardiovascular disease, neurodegenerative diseases (like Alzheimer’s and Parkinson’s), and cancer. Iron accumulation in specific tissues and organs can lead to diseases such as hemochromatosis (a genetic disorder causing excessive iron absorption), liver disease, and heart failure.
  6. Magnesium: This mineral is involved in hundreds of biochemical reactions in the body, including protein synthesis, muscle and nerve function, and blood glucose control.

  7. Calcium: is a crucial mineral that plays numerous roles in the body. It is vital for bone health, heart function, muscle contraction, and nerve signaling. Adequate calcium intake (combined with vitamin D) throughout life helps to build and maintain strong bones, reducing the risk of osteoporosis.
  8. Phosphorus: is an essential mineral that is second only to calcium in terms of abundance in the human body. Phosphorus is a component of nucleic acids (DNA and RNA) and ATP (adenosine triphosphate), which is the body’s primary energy currency. It also plays a role in cell signaling and the regulation of protein activity. Aging is accompanied by a general decline in cellular function, so maintaining adequate phosphorus levels is important for healthy aging.
  9. Selenium: This trace mineral acts as an antioxidant and is involved in DNA repair and the endocrine system. Some studies have suggested a link between higher selenium levels and increased lifespan, although more research is needed.

  10. Zinc: Zinc is vital for immune function and wound healing. It also plays a role in DNA synthesis and repair.

  11. Copper: is an essential trace mineral that plays key roles in several biological functions, including iron metabolism, energy production, neurotransmitter synthesis, and the activation of enzymes important for cardiovascular health. Copper is also a component of antioxidants that protect cells against oxidative damage.
  12. Omega-3 Fatty Acids: Although not technically micronutrients, these fatty acids have anti-inflammatory effects and have been linked to lower risk of chronic diseases associated with aging, such as heart disease.

Test Details

Micronutrients are essential vitamins and minerals required in small quantities by our bodies for various functions such as growth, immune function, brain development, and many more. They play crucial roles in disease prevention and overall wellness. A deficiency or an excess of any of these nutrients can lead to health problems.

Here are some key micronutrients and how they contribute to longevity:

  1. Vitamins: Vitamins such as vitamin D, C, E, and the B-vitamins (especially B6, B9 – folate, and B12) play a pivotal role in longevity. They act as antioxidants, support the immune system, assist in energy production, and contribute to brain health.

  2. Minerals: Minerals such as calcium, magnesium, potassium, and zinc are crucial for bone health, cardiovascular function, immune system, and maintaining a healthy nervous system.

  3. Trace Elements: Elements like selenium, copper, and manganese, needed in very small amounts, serve as antioxidants and play key roles in various metabolic pathways.

  4. Omega-3 Fatty Acids: Technically not classified as micronutrients, omega-3 fatty acids still play a vital role in brain health and have anti-inflammatory properties.

 

Diet plays a crucial role in providing these micronutrients. Eating a varied and balanced diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats is the best way to ensure that you get a wide array of these essential nutrients.

Studies have shown that people who follow a balanced diet rich in these micronutrients tend to have a lower risk of chronic diseases like heart disease, cancer, and diabetes, and also tend to live longer. However, more research is needed to fully understand how individual micronutrients might affect lifespan and longevity, as many factors can influence these outcomes.

In certain circumstances, micronutrient supplementation may be necessary, but it’s essential to do this under the guidance of a healthcare provider. Over-supplementation can have harmful effects and create an imbalance in the body. Moreover, the absorption of these micronutrients often requires a proper balance of different nutrients and depends on overall dietary patterns.

14 Analytes Tested

  1. Vitamin B2 (Riboflavin)
  2. Vitamin B6 (Pyridoxine)
  3. Vitamin B9 (Folate)
  4.  Vitamin B12 (Cobalamin)
  5. Methylated Vitamin B12
  6. Vitamin D 25-OH
  7. Iron
  8. Magnesium
  9. Calcium
  10. Potassium
  11. Phosphorous
  12. Copper
  13. Zinc
  14. Selenium

Vitamin B2, also known as riboflavin, is an essential vitamin that plays a key role in energy production, the metabolism of fats, drugs, and steroids, the maintenance of normal human tissue, and the prevention of certain types of cell damage. While it is crucial for maintaining good health and normal growth, the relationship between vitamin B2 and longevity is a subject of ongoing research.

Oxidative Stress Reduction: Riboflavin is a component of the coenzymes FMN (flavin mononucleotide) and FAD (flavin adenine dinucleotide), which are vital for the function of flavoproteins, including those that work as antioxidants. These flavoproteins help protect cells from oxidative stress, which is a factor in aging and the development of many diseases.

Energy Production: Efficient energy production in the mitochondria is important for long-term health and longevity. Riboflavin is essential for the metabolism of carbohydrates, fats, and proteins into energy, which is critical for maintaining the function of complex cellular processes.

Detoxification Processes: Riboflavin is important for the metabolism of drugs and toxins by the liver, which could contribute to longevity by reducing the exposure of cells to harmful substances.

Homocysteine Metabolism: Vitamin B2 plays a role in the metabolism of homocysteine, an amino acid that at high levels is associated with an increased risk of cardiovascular diseases. By helping to maintain normal homocysteine levels, riboflavin could indirectly contribute to cardiovascular health and longevity.

Gene Regulation and Repair: Riboflavin has been linked to gene expression regulation and the repair of DNA, processes that are important for preventing mutations and protecting against cancer and other age-related diseases.

Neuroprotection: Some evidence suggests riboflavin may have neuroprotective effects, potentially reducing the risk of neurodegenerative diseases that can affect life span.

Mitochondrial Dysfunction: Riboflavin supplementation has been used to treat certain inherited mitochondrial diseases, suggesting its importance in the health of these organelles that are central to cell vitality.

Maintaining adequate levels of riboflavin, along with other vitamins and minerals, is part of a healthy diet and could contribute to overall health, which might indirectly impact longevity. It is always best to aim for a balanced diet to ensure an adequate intake of all essential nutrients.

Folate, also known as vitamin B9, is a water-soluble vitamin that plays a crucial role in many bodily functions, including DNA synthesis and repair, cell division, and growth, production of red and white blood cells, and conversion of carbohydrates into energy. As we age, adequate intake of folate can be particularly important for several reasons:

  1. Cardiovascular Health: Folate, along with vitamins B6 and B12, helps control levels of homocysteine in the blood. High levels of homocysteine are associated with an increased risk of heart disease and stroke. Maintaining proper folate intake can therefore help support heart health.

  2. Cognitive Health: Folate is important for the proper functioning of the brain and for mental and emotional health. There’s some evidence that high folate status is associated with a lower risk of cognitive decline and Alzheimer’s disease in the elderly, although more research is needed in this area.

  3. Mental Health: Deficiencies in folate have been linked to an increased risk of depression and other neuropsychiatric disorders. Some evidence suggests that folate supplementation may enhance the efficacy of antidepressants.

  4. DNA Synthesis and Cell Division: Folate is crucial for DNA synthesis and repair. As we age, the need for cell repair and replacement grows, making the role of folate more important.

 

Folate is naturally present in a wide variety of foods, including vegetables (especially dark green leafy vegetables), fruits and fruit juices, nuts, beans, peas, dairy products, poultry and meat, eggs, seafood, grains.

Despite its wide availability in foods, some people may still not get enough folate from their diets. This can be due to factors like poor diet, alcoholism, or malabsorption issues. In such cases, supplementation might be necessary, but should always be done under the guidance of a healthcare provider. Overconsumption of folate can mask symptoms of vitamin B12 deficiency, which can have serious consequences if not detected and managed.

As always, individual needs can vary, so it’s advisable to consult with a healthcare provider or a registered dietitian for personalized nutrition advice.

 

 

Vitamin B6, also known as pyridoxine, is a water-soluble vitamin that is crucial for several physiological functions. Its roles in the body range from aiding in the metabolism of proteins, fats, and carbohydrates to playing a critical part in cognitive development and immune function. As we age, ensuring an adequate intake of vitamin B6 can be particularly important due to the following reasons:

  1. Cognitive Health: Vitamin B6 plays a vital role in the creation of neurotransmitters, which are chemical messengers that transmit signals between nerve cells. It helps with the production of serotonin, norepinephrine, and melatonin, which are essential for mood regulation and the body’s internal clock. Some research suggests that higher vitamin B6 levels can be linked to better performance on memory tests among older adults.

  2. Immune Health: With age, our immune system function naturally declines, making it harder for the body to fight off infections and diseases. Vitamin B6 is necessary for the creation of white blood cells that are part of the immune response, and a deficiency can lead to a weakened immune system.

  3. Heart Health: Adequate levels of Vitamin B6, along with other B vitamins such as B9 (folate) and B12, can help control levels of homocysteine in the blood. Elevated levels of homocysteine are associated with an increased risk of heart disease.

  4. Eye Health: Vitamin B6, in combination with other nutrients such as B9 and B12, may help reduce the risk of developing age-related macular degeneration, a leading cause of vision loss in older adults.

Vitamin B6 is found in a wide variety of foods including meat, poultry, fish, whole grains, bananas, and some vegetables and nuts. Even though it’s rare to have a vitamin B6 deficiency in developed countries, older people are still at a higher risk due to changes in dietary patterns and decreased absorption capacity.

Therefore, maintaining a balanced diet that includes vitamin B6-rich foods, or possibly considering supplementation under the guidance of a healthcare provider, can be an important part of healthy aging. As always, individual needs can vary, so it’s advisable to consult with a healthcare provider or a registered dietitian for personalized nutrition advice.

Vitamin B12, also known as cobalamin, is a water-soluble vitamin that plays a vital role in brain function and the production of DNA and red blood cells. As we age, our bodies may have more difficulty absorbing this vitamin, which can make older adults more susceptible to a B12 deficiency. Here’s how vitamin B12 impacts the aging process:

  1. Neurological Function: Vitamin B12 is crucial for maintaining healthy nerve cells and it helps in the production of neurotransmitters, chemicals that transmit signals in the brain. Deficiencies can lead to neurological changes including numbness and tingling in the hands and feet, balance problems, and cognitive changes like memory loss and confusion.

  2. Mental Health: Several studies suggest a connection between low levels of vitamin B12 and depression, anxiety, and mood disturbances, although the relationship is not fully understood. Ensuring adequate B12 intake may be a part of maintaining mental health as we age.

  3. Energy Levels: Vitamin B12 is necessary for converting the food we eat into glucose, which provides energy for our bodies. B12 deficiency can therefore lead to fatigue and weakness.

  4. Heart Health: Adequate levels of B12, along with B6 and folate, help control the body’s homocysteine levels. High homocysteine levels are associated with an increased risk of heart disease and stroke.

Vitamin B12 is naturally found in animal products, including fish, meat, poultry, eggs, milk, and milk products. It can also be found in products fortified with B12, such as some varieties of bread and plant-based milk alternatives. B12 is usually well-absorbed by the body when it’s consumed alongside intrinsic factor, a protein our stomachs produce.

 

However, some older adults may produce less intrinsic factor, which can lead to B12 malabsorption and eventually to a deficiency. For this reason, B12 supplementation is often recommended for people over the age of 50. Any supplementation should be done under the guidance of a healthcare provider to ensure appropriate dosage and to monitor for potential side effects.

Given its essential roles in the body and the potential complications of deficiency, vitamin B12 is a key nutrient for healthy aging. As always, individual needs can vary, so it’s advisable to consult with a healthcare provider or a registered dietitian for personalized nutrition advice.

Active Vitamin B12 refers to the biologically active form of vitamin B12, which is also known as methylcobalamin. Vitamin B12 is an essential nutrient that plays a crucial role in various bodily functions, including the formation of red blood cells, neurological health, and DNA synthesis.

Methylcobalamin is one of the two coenzyme forms of vitamin B12, the other being adenosylcobalamin. Methylcobalamin is involved in methylation processes in the body, which are important for various biochemical reactions, including the metabolism of homocysteine, a compound linked to cardiovascular health.

The term “active B12” is often used to emphasize the importance of using the biologically active form of vitamin B12 in supplements or treatments. Methylcobalamin is readily absorbed by the body and does not require conversion in the liver, making it a preferred choice for individuals who may have difficulty metabolizing other forms of vitamin B12.

Supplements containing active B12, such as methylcobalamin, are commonly used to address vitamin B12 deficiencies, support neurological health, and potentially improve energy levels. However, as with any supplement or treatment, it’s important to consult with a healthcare professional before starting any new regimen, especially if you have underlying health conditions or are taking other medications.

Vitamin D is a fat-soluble vitamin that plays numerous critical roles in the body. It’s most well-known for its role in bone health, as it helps the body absorb calcium from the diet. But its role in the body extends beyond just bone health. It is also important for immune function, cell growth, and inflammation regulation. Here’s how Vitamin D impacts aging:

  1. Bone Health: Aging is often accompanied by a decrease in bone density, leading to conditions like osteoporosis. Vitamin D, in combination with calcium, helps maintain strong bones and reduces the risk of fractures.

  2. Muscle Function: Vitamin D is important for muscle health and function, and deficiency can lead to muscle weakness. This is particularly relevant for older adults, who are more likely to experience falls and fractures.

  3. Immune Function: Vitamin D modulates the immune system, and deficiencies have been linked to an increased risk of infections and immune-related disorders. As the immune system naturally weakens with age, maintaining adequate vitamin D levels can help support immune function in older adults.

  4. Mental Health: Some research suggests that low vitamin D levels are associated with a higher risk of cognitive decline, depression, and neurodegenerative diseases like Alzheimer’s, although more studies are needed to confirm these findings.

  5. Cardiovascular Health: Some studies have linked vitamin D deficiency to increased risk of cardiovascular disease, including heart disease and hypertension.

 

Unfortunately, many older adults have suboptimal vitamin D levels. This can be due to a variety of factors, including reduced dietary intake, decreased sunlight exposure (which the body uses to synthesize vitamin D), and reduced kidney function, which impairs the body’s ability to convert vitamin D into its active form.

To maintain adequate vitamin D levels, it’s important to get regular, safe sun exposure and consume vitamin D-rich foods, such as fatty fish, fortified dairy products, and egg yolks. In some cases, supplementation may be necessary, but this should be done under the guidance of a healthcare provider, as excessive vitamin D intake can have harmful effects.

Given the many roles of vitamin D in supporting health and potentially contributing to longevity, it’s important for older adults to ensure they’re getting enough. As always, individual needs can vary, so it’s advisable to consult with a healthcare provider or a registered dietitian for personalized advice.

Iron is a crucial micronutrient that plays a significant role in many biological processes, including oxygen transport, DNA synthesis, and energy metabolism. However, when it comes to aging, the relationship with iron becomes more complex. On the one hand, iron deficiency can lead to anemia, which can cause fatigue, weakness, and cognitive impairment. On the other hand, iron overload can cause damage to organs like the liver and heart and is linked with various age-related diseases.

  1. Iron and Age-Related Diseases: Accumulation of iron in the body can lead to oxidative stress, which contributes to the pathogenesis of numerous age-related diseases, including cardiovascular disease, neurodegenerative diseases (like Alzheimer’s and Parkinson’s), and cancer. Iron accumulation in specific tissues and organs can lead to diseases such as hemochromatosis (a genetic disorder causing excessive iron absorption), liver disease, and heart failure.

  2. Iron and Cognitive Decline: Iron accumulation in the brain has been linked to neurodegenerative diseases like Alzheimer’s and Parkinson’s. Iron can catalyze the production of harmful reactive oxygen species, leading to neuronal damage and death.

  3. Iron and Immune Function: Iron plays a significant role in immune function. Both iron deficiency and iron overload can impair immune response, making individuals more susceptible to infections, which can affect longevity.

  4. Iron and Anemia: Iron deficiency anemia is common in older adults and can lead to fatigue, weakness, and decreased physical functioning. It can also exacerbate the symptoms of other age-related diseases.

Given the complex role of iron in aging and disease, it’s crucial to maintain balanced iron levels. This usually involves eating a diet that includes iron-rich foods (both heme iron from animal sources and non-heme iron from plant sources), along with foods rich in vitamin C to enhance iron absorption. However, iron supplements should only be taken if recommended by a healthcare provider, as excessive iron intake can have harmful effects. It’s also important to have regular check-ups, especially for those with conditions or on medications that may affect iron metabolism, to ensure that iron levels are within the appropriate range.

Magnesium is an essential mineral that plays a crucial role in a variety of bodily functions. It is involved in more than 300 enzymatic reactions, including those responsible for the regulation of heart rhythm, bone strength, immune function, muscle function, and neurological function. Here’s how magnesium impacts the aging process:

  1. Cardiovascular Health: Magnesium is integral to heart health and function. It helps to regulate heart rhythm, assists in the prevention of high blood pressure (a risk factor for heart disease), and has been associated with lower risk of cardiovascular disease.

  2. Bone Health: Approximately 60% of the body’s magnesium is stored in the bones. Magnesium contributes to bone health by influencing the bone cells that regulate bone growth and development. Lower magnesium intake is linked to lower bone mineral density, which increases the risk of osteoporosis and fractures, particularly in older adults.

  3. Mental Health: Magnesium plays a crucial role in the function and regulation of the nervous system, and deficiency can result in neurological symptoms. Some research suggests that higher magnesium intake may reduce the risk of cognitive decline, although more studies are needed to confirm these findings.

  4. Muscle Function: Magnesium is involved in muscle contraction and relaxation, and adequate levels are necessary for optimal physical performance. As muscle mass naturally decreases with age, maintaining adequate magnesium intake can help support muscle health in older adults.

  5. Metabolic Health: Magnesium plays an important role in glucose metabolism and insulin regulation. Lower magnesium levels are associated with an increased risk of developing type 2 diabetes.

 

Magnesium is found in a variety of foods, including green leafy vegetables, legumes, nuts, seeds, and whole grains. Despite its wide availability in foods, dietary surveys suggest that many adults do not get enough magnesium from their diets.

Given the many roles of magnesium in supporting health and potentially contributing to longevity, it’s important for older adults to consume a balanced diet that includes magnesium-rich foods. As always, individual needs can vary, so it’s advisable to consult with a healthcare provider or a registered dietitian for personalized nutrition advice.

Calcium is a crucial mineral that plays numerous roles in the body. It is vital for bone health, heart function, muscle contraction, and nerve signaling. Its association with longevity is primarily linked to these essential functions:

  1. Bone Health: One of the most well-known roles of calcium is in maintaining bone health. Adequate calcium intake (combined with vitamin D) throughout life helps to build and maintain strong bones, reducing the risk of osteoporosis—a disease that makes bones weak and brittle and is a significant cause of disability and decreased quality of life in older adults.

  2. Cardiovascular Health: Calcium is essential for heart function, but there is some controversy over the link between dietary calcium, calcium supplements, and heart health. While adequate dietary calcium is generally considered beneficial for heart health, some studies have suggested that high doses of calcium supplements might increase the risk of heart disease, possibly by contributing to plaque in the arteries. However, this topic is still under scientific debate, and more research is needed to fully understand these potential relationships.

  3. Muscle Function: Calcium is necessary for muscle contraction, including the smooth muscle found in various organ systems. With age, maintaining proper muscle function and strength is critical for maintaining mobility and overall quality of life.

  4. Nerve Function: Calcium plays a vital role in transmitting signals in nerve cells, which is essential for virtually all bodily functions.

When it comes to longevity, ensuring an adequate intake of calcium throughout life is important. However, the source of the calcium and balance with other nutrients is also critical. Dietary calcium, found in foods like dairy products, leafy greens, and certain types of fish, is considered the best source. If supplements are necessary (as determined by a healthcare provider), they should be taken in balance with other nutrients, especially vitamin D, which is necessary for the body to absorb calcium.

Maintaining an overall healthy lifestyle, including a balanced diet and regular exercise, is the best way to utilize calcium’s benefits for longevity. As with any health matter, individual needs and considerations can vary, so it’s always wise to consult with a healthcare provider or a registered dietitian for personalized advice.

Potassium is an essential dietary mineral and electrolyte that plays a vital role in various bodily functions, and it has been studied for its potential impact on health and longevity. Potassium helps to regulate fluid balance, muscle contractions, and nerve signals. A diet rich in potassium is associated with numerous health benefits that may indirectly contribute to longevity.

Cardiovascular Health: Higher potassium intake is linked with lower blood pressure because it helps to balance out the negative effects of sodium. Controlling blood pressure is critical in reducing the risk of stroke and heart disease, which are major causes of death globally.

Stroke Prevention: Several studies suggest that high potassium intake is associated with a reduced risk of stroke, particularly ischemic stroke. This may be due, in part, to potassium’s effects on blood pressure and cardiovascular health.

Bone Health: Adequate potassium, especially in the context of a diet that also includes calcium and magnesium, is associated with improved bone density. Maintaining strong bones can reduce the risk of fractures and osteoporosis, contributing to better mobility and health in older age.

Muscle and Nerve Function: Potassium is crucial for normal muscle and nerve function. It is involved in the regulation of muscle contractions and helps to prevent muscle cramps, which can affect quality of life and physical activity levels.

Kidney Stones: Higher dietary potassium intake has been linked to a reduced risk of kidney stones. Potassium may help to reduce the formation of kidney stones by decreasing urinary calcium excretion.

Cell Function: Potassium plays a role in maintaining the electrical conductivity of cells, particularly heart muscle cells. Proper functioning of cells is critical for overall health and prevention of arrhythmias.

Metabolic Health: There is evidence to suggest that potassium can influence metabolic health, including the regulation of blood sugar and insulin sensitivity, which are important factors in the prevention of metabolic syndrome and type 2 diabetes.

While potassium can contribute to health and potentially affect longevity, it’s important to consume it in appropriate amounts. Both deficiency and excessive intake can lead to health issues. Hyperkalemia, or too much potassium in the blood, can be dangerous and cause heart rhythm problems, especially for individuals with kidney dysfunction who cannot properly excrete potassium.

The recommended daily intake of potassium for adults is around 2,600 to 3,400 milligrams per day, according to various health authorities, but it’s best to consult with a healthcare provider for individual recommendations. Potassium is abundant in fruits and vegetables, such as bananas, oranges, potatoes, and leafy greens, making a diet rich in these foods beneficial for health and potentially for longevity as well.

In summary, while no single nutrient is the key to longevity, potassium is an important part of a balanced diet that supports several critical bodily functions, which can promote health and potentially contribute to a longer life.

Phosphorus is an essential mineral that is second only to calcium in terms of abundance in the human body. It plays key roles in numerous biological functions, including bone health, energy production, and cell function. Here’s how phosphorus can impact the aging process:

  1. Bone Health: About 85% of the body’s phosphorus is found in bones and teeth. Phosphorus, along with calcium, is crucial for maintaining bone strength and structure. Inadequate phosphorus intake can lead to decreased bone mineral density, increasing the risk of fractures and osteoporosis, particularly in older adults.

  2. Cell Function: Phosphorus is a component of nucleic acids (DNA and RNA) and ATP (adenosine triphosphate), which is the body’s primary energy currency. It also plays a role in cell signaling and the regulation of protein activity. Aging is accompanied by a general decline in cellular function, so maintaining adequate phosphorus levels is important for healthy aging.

  3. Kidney Function: As people age, kidney function often declines, affecting the body’s ability to excrete phosphorus. This can lead to hyperphosphatemia (high phosphorus levels in the blood), which is associated with cardiovascular disease and mortality in people with chronic kidney disease.

  4. Cardiovascular Health: High phosphorus levels have been linked to an increased risk of cardiovascular disease, possibly due to the development of vascular calcification (hardening of the arteries).

The recommended dietary allowance (RDA) for phosphorus is 700 mg per day for adults. Most people in developed countries consume more than this amount because phosphorus is found in many foods, including meat, poultry, fish, dairy products, and processed foods.

Given the importance of phosphorus to numerous aspects of health and its potential risks when levels are too high, it’s important for older adults to maintain a balanced intake of this mineral. As with any nutrient, individual needs can vary depending on a variety of factors, so it’s always wise to consult with a healthcare provider for personalized advice.

Zinc is an essential trace mineral with various roles in cellular metabolism. It is involved in the catalytic activity of approximately 300 enzymes and plays a role in immune function, protein synthesis, wound healing, DNA synthesis, and cell division. As we age, the significance of maintaining adequate zinc levels becomes more apparent due to its numerous health benefits:

  1. Immune function: Zinc is known to play a crucial role in the immune system. A deficiency can lead to a weakened immune response, making an individual more susceptible to infections. Aging is associated with a natural decline in immune function (a phenomenon known as immunosenescence), and maintaining adequate zinc levels is important to support healthy immune function in older adults.

  2. Skin Health and Wound Healing: Zinc plays a significant role in maintaining skin integrity and promoting wound healing. This becomes increasingly important with age as skin becomes thinner and the body’s ability to heal wounds slows down.

  3. Sensory Function: Zinc is crucial for maintaining the health of the sensory organs, particularly taste and smell. Zinc deficiency can lead to a decrease in these senses, which is already a common issue among older adults.

  4. Mental Health: Some research suggests that zinc may have neuroprotective properties, and inadequate levels may contribute to the onset of neuropsychiatric disorders, particularly in older adults.

  5. Antioxidant properties: Zinc acts as an antioxidant and stabilizes membranes, which can help prevent oxidative damage, a key contributor to aging and the development of chronic diseases like heart disease and cancer.

Most people can get adequate amounts of zinc through a balanced diet that includes good sources like meat, shellfish, legumes, seeds, nuts, dairy products, eggs, and whole grains. However, some older adults may have difficulty absorbing zinc or getting enough from their diet. In such cases, a healthcare provider may recommend a dietary supplement. But it’s important to remember that excessive zinc supplementation can lead to toxicity and can interfere with the absorption of other essential minerals like copper.

Given its important roles in the body and the potential implications of deficiency, zinc is a key nutrient for healthy aging. Always consult with a healthcare provider or a registered dietitian for personalized nutrition advice.

Copper is an essential trace mineral that plays key roles in several biological functions, including iron metabolism, energy production, neurotransmitter synthesis, and the activation of enzymes important for cardiovascular health. Copper is also a component of antioxidants that protect cells against oxidative damage. Here is how copper can impact the aging process:

  1. Antioxidant Function: Copper is a component of the antioxidant enzyme superoxide dismutase, which protects cells from oxidative damage caused by free radicals. Oxidative stress can contribute to aging and various age-related diseases, including heart disease, cancer, and neurodegenerative disorders.

  2. Neurological Health: Copper is involved in the synthesis of neurotransmitters, chemicals that brain cells use to communicate with each other. Disruptions in copper metabolism have been implicated in neurodegenerative diseases like Alzheimer’s and Parkinson’s.

  3. Cardiovascular Health: Copper is needed for the activation of certain enzymes that help maintain the health of the cardiovascular system. Some research suggests that copper deficiency may increase the risk of cardiovascular disease.

  4. Bone Health: Copper plays a role in the formation of collagen, a protein that is an essential component of bones, skin, and connective tissue. Copper deficiency can affect bone health and contribute to conditions like osteoporosis.

  5. Immune Function: Copper influences the functioning of the immune system. Copper deficiency can impair immune function, making individuals more susceptible to infections.

Although copper is essential for health, too much copper can be harmful. High levels of

copper can cause oxidative damage and have been linked to neurodegenerative diseases. Wilson’s disease, for example, is a genetic disorder that leads to excessive copper accumulation in the body, causing neurological and liver damage.

Given the role of copper in numerous aspects of health, it’s important to maintain a balanced intake of this mineral. Copper is found in a wide variety of foods, including organ meats, shellfish, nuts, seeds, whole grains, and dark chocolate. However, the bioavailability of copper can be affected by other dietary factors, and individual needs can vary. As always, it’s advisable to consult with a healthcare provider for personalized nutrition advice.

Selenium is a trace element that is crucial for many bodily processes, including cognitive function, a healthy immune system, and fertility in both men and women. It contributes to longevity and healthy aging in several ways:

  1. Antioxidant Properties: Selenium is a critical component of several enzymes (glutathione peroxidases, thioredoxin reductase, and others) that help reduce oxidative stress in the body by neutralizing excess free radicals and preventing inflammation. This is important because oxidative stress can lead to chronic conditions like heart disease and cancer, as well as aging-related physiological changes.

  2. Thyroid Function: Selenium contributes to the health of the thyroid gland, which regulates metabolism and controls growth and development. It helps protect the thyroid against oxidative damage and is necessary for the production of thyroid hormones. Disruptions in thyroid function can impact many aspects of health, including energy levels, weight, and mood.

  3. Immune System Function: Selenium helps support the immune system, which can become weaker with age, leaving older adults more susceptible to illnesses. Adequate selenium levels can help ensure a robust response to infections.

  4. Brain Health: Some research suggests a potential role for selenium in supporting brain health, including in the context of cognitive decline and neurodegenerative diseases, though more research is needed in this area.

It’s worth noting that while adequate selenium is necessary for health, too much selenium can lead to toxicity, known as selenosis. Symptoms include gastrointestinal upset, hair loss, white blotchy nails, garlic breath odor, fatigue, irritability, and mild nerve damage. 

Selenium is found in a variety of foods, the richest sources being Brazil nuts, seafood, and organ meats. The amount of selenium in other sources, like meats, bread, and vegetables, depends on the selenium content of the soil where the plants were grown or where the animals were raised.

Given the various roles of selenium in supporting health and potentially contributing to longevity, it’s important for older adults to consume a balanced diet that includes selenium-rich foods. As always, individual needs can vary, so it’s advisable to consult with a healthcare provider or a registered dietitian for personalized nutrition advice.

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