Longevity Oxidative Stress Blood Test
$449.00
Redox balance and oxidative stress are central themes in the study of longevity and the aging process. Redox balance refers to the state of equilibrium between oxidation and reduction reactions within a cell or organism. These chemical reactions are crucial for energy production, detoxification, and cellular signaling processes. Oxidative stress occurs when there’s an imbalance in this system—specifically, when the production of reactive oxygen species (ROS) exceeds the body’s ability to neutralize and eliminate them. While ROS are natural by-products of oxygen metabolism and play roles in cell signaling and homeostasis, excessive ROS levels can damage proteins, lipids, and DNA, contributing to cellular aging and the onset of age-related diseases such as cardiovascular diseases, diabetes, neurodegenerative disorders, and cancer.
This test measures biomarkers that are indicators of the level of oxidation and the REDOX balance.
14 Analytes Tested: GSH/GSSG, 8-Isoprostane, Malondialdehyde (MDA), NAD/NADH, inducible Nitric Oxide Synthase (iNOS), Reactive Oxygen Species (ROS), Peroxidases, Superoxide Dismutases (SODs), Advanced Oxidation Protein Products (AOPP), Total Antioxidant Capacity (TAC), Protein Carbonyls, 8-Hydroxy-2′-deoxyguanosine (8-OHdG)
Description
Oxidative stress plays a complex role in the aging process and longevity. It occurs when there’s an imbalance between the production of reactive oxygen species (ROS) and the body’s ability to detoxify these reactive intermediates or to repair the resulting damage. ROS are by-products of normal cellular metabolic processes, but excessive ROS can lead to cell and tissue damage, contributing to aging and the development of age-related diseases such as cardiovascular diseases, diabetes, cancer, and neurodegenerative disorders.
However, the relationship between oxidative stress and longevity is not straightforward. While high levels of oxidative stress can accelerate the aging process and contribute to disease, a moderate increase in ROS can actually have beneficial effects through a process known as hormesis. Hormesis refers to a biological phenomenon where a beneficial effect (such as improved health, stress tolerance, growth, or longevity) results from exposure to low doses of an agent that is otherwise toxic or lethal when given at higher doses. In the context of oxidative stress, low levels of ROS can stimulate protective, adaptive responses in cells that enhance their ability to cope with greater stresses, potentially leading to increased lifespan and healthspan.
